Title: Book The Best Hotels in Upstate South Carolina for 2026 from CA $98 - Fully Refundable Options - Expedia.ca

[Upstate South Carolina Travel Guide](https://expedia.ca/Upstate-South-Carolina.dx6057939)[Vacation Rentals in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Vacation-Rentals.d6057939.Travel-Guide-VacationRentals)[Flights to Upstate South Carolina](https://expedia.ca/Cheap-Flights-To-Upstate-South-Carolina.d6057939.Travel-Guide-Flights)[Things to do in Upstate South Carolina](https://expedia.ca/Things-To-Do-In-Upstate-South-Carolina.d6057939.Travel-Guide-Activities)[Upstate South Carolina Car Rentals](https://expedia.ca/Car-Rentals-In-Upstate-South-Carolina.d6057939.Car-Rental-Guide)[Upstate South Carolina Vacation Packages](https://expedia.ca/Upstate-South-Carolina.d6057939.Destination-Travel-Guides)

![Greenville - Spartanburg](https://images.trvl-media.com/place/6035267/cb556cb0-09f4-48a1-92a0-474aceebaeea.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by Visit Greenville, South Carolina

![](https://images.trvl-media.com/place/6035267/cb556cb0-09f4-48a1-92a0-474aceebaeea.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Go beyond your typical stay in Upstate South Carolina

Spa

[](https://www.expedia.ca/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America&regionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2026-04-09&d1=2026-04-09&endDate=2026-04-11&d2=2026-04-11&amenities=SPA_ON_SITE)

Resort

[](https://www.expedia.ca/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America&regionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2026-04-09&d1=2026-04-09&endDate=2026-04-11&d2=2026-04-11&lodging=HOTEL_RESORT)

Cabin

[](https://www.expedia.ca/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America&regionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2026-04-09&d1=2026-04-09&endDate=2026-04-11&d2=2026-04-11&lodging=CABIN)

Hot tub

[](https://www.expedia.ca/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America&regionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2026-04-09&d1=2026-04-09&endDate=2026-04-11&d2=2026-04-11&amenities=HOT_TUB)

Family friendly

[](https://www.expedia.ca/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America&regionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2026-04-09&d1=2026-04-09&endDate=2026-04-11&d2=2026-04-11&travelerType=family_friendly)

Pool

[](https://www.expedia.ca/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America&regionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2026-04-09&d1=2026-04-09&endDate=2026-04-11&d2=2026-04-11&amenities=POOL)

Farm

[](https://www.expedia.ca/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America&regionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2026-04-09&d1=2026-04-09&endDate=2026-04-11&d2=2026-04-11&lodging=AGRITOURISM)

Pet friendly

[](https://www.expedia.ca/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America&regionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2026-04-09&d1=2026-04-09&endDate=2026-04-11&d2=2026-04-11&amenities=PETS)

Cottage

[](https://www.expedia.ca/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America&regionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2026-04-09&d1=2026-04-09&endDate=2026-04-11&d2=2026-04-11&lodging=COTTAGE)

Apart­ment

[](https://www.expedia.ca/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America&regionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2026-04-09&d1=2026-04-09&endDate=2026-04-11&d2=2026-04-11&lodging=APARTMENT)

Condo

[](https://www.expedia.ca/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America&regionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2026-04-09&d1=2026-04-09&endDate=2026-04-11&d2=2026-04-11&lodging=CONDO)

## Check prices for these dates

Tonight

[Mar 26 - Mar 27](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2026-03-26&endDate=2026-03-27&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Mar 27 - Mar 28](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2026-03-27&endDate=2026-03-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Mar 27 - Mar 29](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2026-03-27&endDate=2026-03-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Apr 3 - Apr 5](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2026-04-03&endDate=2026-04-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Upstate South Carolina hotels

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/430000/424900/424882/cd259adf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/430000/424900/424882/573947b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/430000/424900/424882/0304ce09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/1000000/430000/424900/424882/1ccff62b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn Gaffney

[](https://www.expedia.ca/Gaffney-Hotels-Hampton-Inn-Gaffney.h424882.Hotel-Information)

Gaffney

8.8/10

Excellent

(693 reviews)

"Would stay again breakfast was amazing "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Theresa

CA $124

CA $135 total

includes taxes & fees

Apr 19 - Apr 20

[](https://www.expedia.ca/Gaffney-Hotels-Hampton-Inn-Gaffney.h424882.Hotel-Information)

![Free daily full breakfast](https://images.trvl-media.com/lodging/72000000/71520000/71515100/71515054/589dc000.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/72000000/71520000/71515100/71515054/b9808144.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/72000000/71520000/71515100/71515054/a5e4dea1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, down comforters, desk, blackout drapes](https://images.trvl-media.com/lodging/72000000/71520000/71515100/71515054/39d93722.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express Gaffney by IHG

[](https://www.expedia.ca/Gaffney-Hotels-Holiday-Inn-Express-Gaffney.h71515054.Hotel-Information)

Gaffney

8.8/10

Excellent

(459 reviews)

"Very clean and staff the super kind and friendly 10/10 stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kevin

CA $127

CA $139 total

includes taxes & fees

Mar 29 - Mar 30

[](https://www.expedia.ca/Gaffney-Hotels-Holiday-Inn-Express-Gaffney.h71515054.Hotel-Information)

![Premium bedding, in-room safe, individually furnished, laptop workspace](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/afe0f510.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cabin, 1 Bedroom, Courtyard View | Front of property](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/f825207a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Seasonal outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/b26b87ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, in-room safe, individually furnished, laptop workspace](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/4d5d913d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Carolina Camp Cedar

[](https://www.expedia.ca/Pickens-Hotels-Carolina-Camp-Cedar.h122099740.Hotel-Information)

Pickens

10/10

Exceptional

(3 reviews)

"The cottage was clean, staff was so friendly, our stay was quiet and peaceful… it was perfect! Definitely planning to stay there again!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Katlynn

CA $135

CA $265 total

includes taxes & fees

Mar 30 - Mar 31

[](https://www.expedia.ca/Pickens-Hotels-Carolina-Camp-Cedar.h122099740.Hotel-Information)

![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/375f69b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/f6f7c8c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Business centre](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/16b3def6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/eab53b27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Quality Inn Seneca Clemson Area US-123

[](https://www.expedia.ca/Anderson-Hotels-Quality-Inn-Seneca-US-123.h76800.Hotel-Information)

Downtown

8.0/10

Very good

(689 reviews)

"Room was very clean, the grounds was in well taken care of, was safe. Overall a good place to stay."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Billy

CA $107

CA $126 total

includes taxes & fees

Apr 16 - Apr 17

[](https://www.expedia.ca/Anderson-Hotels-Quality-Inn-Seneca-US-123.h76800.Hotel-Information)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/69000000/68980000/68975500/68975422/d93f55e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/69000000/68980000/68975500/68975422/9d9a13cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/69000000/68980000/68975500/68975422/799eeb33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/69000000/68980000/68975500/68975422/d45e119a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn Greer Greenville, SC

[](https://www.expedia.ca/Greer-Hotels-Hampton-Inn-Greer-Greenville.h68975422.Hotel-Information)

Greer

9.6/10

Exceptional

(441 reviews)

"Parking garage for hotel guests, location was great, hotel was clean, staff was great. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tyler

CA $191

CA $209 total

includes taxes & fees

Apr 3 - Apr 4

[](https://www.expedia.ca/Greer-Hotels-Hampton-Inn-Greer-Greenville.h68975422.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/b0e15e12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/w5755h3840x5y0-5e0099e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![37-inch flat-screen TV with cable channels, TV, pay movies](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/8837843b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 2 Double Beds, Non Smoking | Living area](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/536a8160.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Embassy Suites Greenville Golf Resort & Conference Center

[](https://www.expedia.ca/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information)

Greenville

9.0/10

Wonderful

(1,120 reviews)

"Clean room and great Breakfast "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tara

CA $151

CA $166 total

includes taxes & fees

Apr 5 - Apr 6

[](https://www.expedia.ca/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information)

![Front of property - evening/night](https://images.trvl-media.com/lodging/23000000/22520000/22513500/22513453/5971f25f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Gazebo](https://images.trvl-media.com/lodging/23000000/22520000/22513500/22513453/1fc30205.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fireplace](https://images.trvl-media.com/lodging/23000000/22520000/22513500/22513453/92684d2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily local cuisine breakfast](https://images.trvl-media.com/lodging/23000000/22520000/22513500/22513453/9966f479.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.

[](https://www.expedia.ca/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Woodruff-Rd.h22513453.Hotel-Information)

Greenville

8.8/10

Excellent

(149 reviews)

"Great place to stay."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Roymond

CA $104

CA $118 total

includes taxes & fees

Mar 29 - Mar 30

[](https://www.expedia.ca/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Woodruff-Rd.h22513453.Hotel-Information)

![Golf](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/ad943919.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property - evening/night](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/63d829f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Aerial view](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/0aec11f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Seasonal outdoor pool, open 10:00 AM to 9:00 PM, free cabanas](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/8fa71ed7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Clemson University's James F. Martin Inn

[](https://www.expedia.ca/Anderson-Hotels-Clemson-Universitys-James-F-Martin-Inn.h8474950.Hotel-Information)

Clemson

9.4/10

Exceptional

(988 reviews)

"Excellent stay "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Elliott

CA $205

CA $228 total

includes taxes & fees

Apr 12 - Apr 13

[](https://www.expedia.ca/Anderson-Hotels-Clemson-Universitys-James-F-Martin-Inn.h8474950.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/66000000/65710000/65708700/65708685/0f86ef1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/66000000/65710000/65708700/65708685/w3840h2558x0y0-944f5cdf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![32-inch plasma TV with cable channels, TV](https://images.trvl-media.com/lodging/66000000/65710000/65708700/65708685/284160fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/66000000/65710000/65708700/65708685/6d084ccc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Home2 Suites by Hilton Anderson Downtown

[](https://www.expedia.ca/Anderson-Hotels-Home2-Suites-By-Hilton-Anderson-Downtown.h65708685.Hotel-Information)

Anderson

9.4/10

Exceptional

(232 reviews)

"Room was great and the staff polite and helpful "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Sheila D

CA $193

CA $215 total

includes taxes & fees

Apr 26 - Apr 27

[](https://www.expedia.ca/Anderson-Hotels-Home2-Suites-By-Hilton-Anderson-Downtown.h65708685.Hotel-Information)

![BBQ/picnic area](https://images.trvl-media.com/lodging/1000000/110000/105600/105540/fd542db9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pillowtop beds, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/110000/105600/105540/c83ed6f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/110000/105600/105540/a7c81686.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/110000/105600/105540/9b9d3bd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Best Western Travelers Rest Greenville

[](https://www.expedia.ca/Travelers-Rest-Hotels-Best-Western-Travelers-Rest-Greenville.h105540.Hotel-Information)

Travelers Rest

7.6/10

Good

(1,001 reviews)

"The area, town and shops were wonderful. It was a short distance to the Swamp Rabbit trail. Place was comfortable, clean and friendly"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Paul

CA $127

CA $140 total

includes taxes & fees

Apr 14 - Apr 15

[](https://www.expedia.ca/Travelers-Rest-Hotels-Best-Western-Travelers-Rest-Greenville.h105540.Hotel-Information)

![Free breakfast](https://images.trvl-media.com/lodging/4000000/3630000/3629900/3629858/e417f297.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/4000000/3630000/3629900/3629858/60389240.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, blackout drapes, iron/ironing board, rollaway beds](https://images.trvl-media.com/lodging/4000000/3630000/3629900/3629858/66ea89ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Business centre](https://images.trvl-media.com/lodging/4000000/3630000/3629900/3629858/70604dbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn Anderson/ Alliance Business Park

[](https://www.expedia.ca/Anderson-Hotels-Hampton-Inn-Anderson-North.h3629858.Hotel-Information)

Anderson

9.2/10

Wonderful

(830 reviews)

"Staff were so helpful , place was clean and food spots near by"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

osiry

CA $150

CA $167 total

includes taxes & fees

Apr 19 - Apr 20

[](https://www.expedia.ca/Anderson-Hotels-Hampton-Inn-Anderson-North.h3629858.Hotel-Information)

![Lobby lounge](https://images.trvl-media.com/lodging/1000000/120000/119100/119074/5cc3b6ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/1000000/120000/119100/119074/0d8d0617.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/120000/119100/119074/95c63f23.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/120000/119100/119074/51a7c4d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Fairfield Inn & Suites by Marriott Greenville Simpsonville

[](https://www.expedia.ca/Simpsonville-Hotels-Fairfield-Inn-Suites-By-Marriott-Greenville-Simpsonville.h119074.Hotel-Information)

Simpsonville

9.0/10

Wonderful

(686 reviews)

"Great location, great service, great facility "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

henry

CA $128

CA $140 total

includes taxes & fees

Apr 19 - Apr 20

[](https://www.expedia.ca/Simpsonville-Hotels-Fairfield-Inn-Suites-By-Marriott-Greenville-Simpsonville.h119074.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/990000/988800/988782/67f2e81b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 restaurants, breakfast, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/990000/988800/988782/ea82fa69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/990000/988800/988782/e439dee7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/1000000/990000/988800/988782/355528af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Spartanburg Marriott

[](https://www.expedia.ca/Spartanburg-Hotels-Spartanburg-Marriott.h988782.Hotel-Information)

Spartanburg

8.6/10

Excellent

(1,002 reviews)

"Comfy bed, friendly, helpful staff, close to venue and other restaurants and bars close"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Timothy

CA $163

CA $181 total

includes taxes & fees

Apr 26 - Apr 27

[](https://www.expedia.ca/Spartanburg-Hotels-Spartanburg-Marriott.h988782.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/1000000/850000/848800/848780/9bab6d34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/850000/848800/848780/0160650e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/850000/848800/848780/227b33b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/850000/848800/848780/3f88a754.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

[](https://www.expedia.ca/Anderson-Hotels-Holiday-Inn-Express-Hotel-Suites-Anderson-I-85.h848780.Hotel-Information)

Anderson

9.0/10

Wonderful

(601 reviews)

"Clean rooms, friendly staff, great breakfast options!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Lauren

CA $153

CA $170 total

includes taxes & fees

Mar 29 - Mar 30

[](https://www.expedia.ca/Anderson-Hotels-Holiday-Inn-Express-Hotel-Suites-Anderson-I-85.h848780.Hotel-Information)

![Free breakfast](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3837h2558x3y3-4efd29d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/282fab11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Down comforters, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3837h2557x3y4-ce9cc597.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3837h2558x3y3-f00c0668.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Best Western Plus Clemson Hotel & Conference Center

[](https://www.expedia.ca/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information)

Clemson

8.2/10

Very good

(1,000 reviews)

"Clean room/friendly staff/good breakfast"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Gisela M.

CA $149

CA $165 total

includes taxes & fees

Apr 1 - Apr 2

[](https://www.expedia.ca/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/49000000/48260000/48251500/48251408/b3b1b4a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/49000000/48260000/48251500/48251408/1ac2fb4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/49000000/48260000/48251500/48251408/0e19a728.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/49000000/48260000/48251500/48251408/84ae320a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Tru by Hilton Spartanburg

[](https://www.expedia.ca/Greenville-Spartanburg-Hotels-Tru-By-Hilton-Spartanburg.h48251408.Hotel-Information)

Spartanburg

9.2/10

Wonderful

(866 reviews)

"Nice stay "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Krystal

CA $126

CA $140 total

includes taxes & fees

Apr 19 - Apr 20

[](https://www.expedia.ca/Greenville-Spartanburg-Hotels-Tru-By-Hilton-Spartanburg.h48251408.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/w4000h2662x0y0-18bf21d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/cc35e730.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/2c84c92f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/72000000/71600000/71594700/71594655/e45ab30f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Fairfield Inn & Suites Seneca Clemson Univ Area 

[](https://www.expedia.ca/Seneca-Hotels-Fairfield-Inn-Suites-By-Marriott-Seneca.h71594655.Hotel-Information)

Seneca

9.4/10

Exceptional

(214 reviews)

"Hotel and room were super clean. Hotel is fairly new and it shows. Nice view of Lake Keowee. Breakfast was quite good & excellent coffee. Would definitely stay there again. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Matthew

CA $165

CA $182 total

includes taxes & fees

Mar 30 - Mar 31

[](https://www.expedia.ca/Seneca-Hotels-Fairfield-Inn-Suites-By-Marriott-Seneca.h71594655.Hotel-Information)

![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/30000/26900/26875/54b1a852.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26900/26875/d789a59c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/26900/26875/ea1edcbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26900/26875/7e082995.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Quality Inn Clinton - Laurens I-26

[](https://www.expedia.ca/Clinton-Hotels-Quality-Inn-Clinton.h26875.Hotel-Information)

Clinton

7.4/10

Good

(538 reviews)

"Very friendly staff and places to eat close by! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Burit

CA $92

CA $108 total

includes taxes & fees

Apr 11 - Apr 12

[](https://www.expedia.ca/Clinton-Hotels-Quality-Inn-Clinton.h26875.Hotel-Information)

![Aerial view](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/db449d90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Aerial view](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/ad742419.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/6abd26aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/41000000/40220000/40217400/40217319/91e6d418.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Lakeside Lodge Clemson

[](https://www.expedia.ca/Anderson-Hotels-Lakeside-Lodge-Clemson.h40217319.Hotel-Information)

Seneca

9.0/10

Wonderful

(1,000 reviews)

"Great place and location, great mattress, "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jeffrey

CA $150

CA $186 total

includes taxes & fees

Apr 7 - Apr 8

[](https://www.expedia.ca/Anderson-Hotels-Lakeside-Lodge-Clemson.h40217319.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/3000000/2550000/2544000/2543902/63e5477d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free buffet breakfast](https://images.trvl-media.com/lodging/3000000/2550000/2544000/2543902/128bf160.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 King Bed (Additional Living Area)](https://images.trvl-media.com/lodging/3000000/2550000/2544000/2543902/638ff369.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/3000000/2550000/2544000/2543902/42e16252.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

[](https://www.expedia.ca/Spartanburg-Hotels-Holiday-Inn-Express-Hotel-Suites-Spartanburg-North.h2543902.Hotel-Information)

Spartanburg

8.6/10

Excellent

(886 reviews)

"Clean room, helpful staff. Great breakfast! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Christine

CA $143

CA $159 total

includes taxes & fees

Apr 12 - Apr 13

[](https://www.expedia.ca/Spartanburg-Hotels-Holiday-Inn-Express-Hotel-Suites-Spartanburg-North.h2543902.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-04-09&endDate=2026-04-10&regionId=6057939&adults=2&sort=RECOMMENDED&openPlayBack=true)

## Vacation Rentals in Upstate South Carolina

Cabin

![Premium bedding, in-room safe, individually furnished, laptop workspace](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/afe0f510.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cabin, 1 Bedroom, Courtyard View | Front of property](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/f825207a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Seasonal outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/b26b87ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, in-room safe, individually furnished, laptop workspace](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/4d5d913d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Carolina Camp Cedar

[](https://www.expedia.ca/Pickens-Hotels-Carolina-Camp-Cedar.h122099740.Hotel-Information)

Pickens

10/10

Exceptional

(3 reviews)

"The cottage was clean, staff was so friendly, our stay was quiet and peaceful… it was perfect! Definitely planning to stay there again!"

[](https://www.expedia.ca/Pickens-Hotels-Carolina-Camp-Cedar.h122099740.Hotel-Information)

Apartment

![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/108000000/107980000/107978100/107978043/d4764610.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/108000000/107980000/107978100/107978043/26081583.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/108000000/107980000/107978100/107978043/a232b415.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/108000000/107980000/107978100/107978043/53b6a5d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Serene Travelers Rest Apartment: 7 Mi to Downtown!

[](https://www.expedia.ca/Travelers-Rest-Hotels-Serene-Travelers-Rest-Apartment-7-Mi-To-Downtown.h107978043.Hotel-Information)

Travelers Rest

10/10

Exceptional

(1 review)

"The best time ever. My wife and I enjoyed our Honeymoon and stay here. We will come back every year for our Anniversary now and also to vacation here. The area was beautiful, quiet, and safe. We had everything we needed. No other vacation spot in South Carolina can compete. Thank you for our wonderful stay and perfect memories! "

[](https://www.expedia.ca/Travelers-Rest-Hotels-Serene-Travelers-Rest-Apartment-7-Mi-To-Downtown.h107978043.Hotel-Information)

Aparthotel

![Trailside Wedge Cottage | Terrace/patio](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/346fcb37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/87440d66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Vista Wedge Cottage | Private kitchen](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/9304eefe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Trailside Wedge Cottage | Living area](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/f19cdb36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Station by Compo Hotels

[](https://www.expedia.ca/Travelers-Rest-Hotels-The-Station-By-Compo-Hotels.h88361952.Hotel-Information)

Travelers Rest

10/10

Exceptional

(18 reviews)

"great place perfect for more privacy vs. a standard hotel"

[](https://www.expedia.ca/Travelers-Rest-Hotels-The-Station-By-Compo-Hotels.h88361952.Hotel-Information)

Aparthotel

![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/70000000/69720000/69716800/69716747/61217476.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/70000000/69720000/69716800/69716747/2d11b158.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![BBQ/picnic area](https://images.trvl-media.com/lodging/70000000/69720000/69716800/69716747/cc01b08f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/70000000/69720000/69716800/69716747/002ffe20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### stayAPT Suites Greenville-Haywood Mall

[](https://www.expedia.ca/Greenville-Hotels-StayAPT-Suites-Greenville-Haywood-Mall.h69716747.Hotel-Information)

Greenville

9.0/10

Wonderful

(212 reviews)

"Nice gym, good breakfast and the rooms are clean and well appointed. Good hotel stayed one night with my family "

[](https://www.expedia.ca/Greenville-Hotels-StayAPT-Suites-Greenville-Haywood-Mall.h69716747.Hotel-Information)

Mobile Home

![Cabin, 2 Bedrooms, Non Smoking (No Pets, Linens Included) | In-room dining](https://images.trvl-media.com/lodging/10000000/9130000/9126600/9126575/e62d89db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV](https://images.trvl-media.com/lodging/10000000/9130000/9126600/9126575/dcda994e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV](https://images.trvl-media.com/lodging/10000000/9130000/9126600/9126575/44e61f9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room](https://images.trvl-media.com/lodging/10000000/9130000/9126600/9126575/6f5c7f95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Carolina Landing RV Resort - Caravan Park

[](https://www.expedia.ca/Fair-Play-Hotels-Carolina-Landing-RV-Resort-Caravan-Park.h9126575.Hotel-Information)

Fair Play

7.6/10

Good

(47 reviews)

"Lake "

[](https://www.expedia.ca/Fair-Play-Hotels-Carolina-Landing-RV-Resort-Caravan-Park.h9126575.Hotel-Information)

Cottage

![Signature Cottage, 2 Bedrooms | Living room](https://images.trvl-media.com/lodging/90000000/89510000/89502700/89502605/a4df93b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Signature Cottage, 2 Bedrooms | Private kitchen](https://images.trvl-media.com/lodging/90000000/89510000/89502700/89502605/w775h924x3y0-5b08ac43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/90000000/89510000/89502700/89502605/b86441f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Signature Cottage, 2 Bedrooms | Private kitchen](https://images.trvl-media.com/lodging/90000000/89510000/89502700/89502605/0d77f138.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Clemson Memorabilia House

[](https://www.expedia.ca/Clemson-Hotels-Clemson-Memorabilia-House.h89502605.Hotel-Information)

Clemson

9.8/10

Exceptional

(9 reviews)

"We enjoyed our stay, it was the perfect size for our family of four. "

[](https://www.expedia.ca/Clemson-Hotels-Clemson-Memorabilia-House.h89502605.Hotel-Information)

Apartment

![Deluxe Two Bedroom (Self Check-in with Virtual Front Desk) | Living area](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/5e1376bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![One Bedroom (Self Check-in with Virtual Front Desk)](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/21618793.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Two Bedroom (Self Check-in with Virtual Front Desk) | Private kitchen](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/d192b91d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Two Bedroom (Self Check-in with Virtual Front Desk) | Living area](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/fb93f07a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Mint House Greenville Downtown by Kasa

[](https://www.expedia.ca/Greenville-Spartanburg-Hotels-Mint-House-Downtown-Greenville.h38593248.Hotel-Information)

Greenville Downtown

9.2/10

Wonderful

(805 reviews)

"Room was very roomy with plenty of extra linens. Very accessible to shopping and restaurants."

[](https://www.expedia.ca/Greenville-Spartanburg-Hotels-Mint-House-Downtown-Greenville.h38593248.Hotel-Information)

Cottage

![Cottage (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/112000000/111930000/111929300/111929202/803858a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cottage (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/112000000/111930000/111929300/111929202/5001142e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cottage (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/112000000/111930000/111929300/111929202/02c27678.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cottage (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/112000000/111930000/111929300/111929202/55d24103.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### < 3 Mi to Dtwn: Modern Cottage in Greenville!

[](https://www.expedia.ca/Greenville-Hotels-3-Mi-To-Dtwn-Modern-Cottage-In-Greenville.h111929202.Hotel-Information)

Greenville

10/10

Exceptional

(1 review)

[](https://www.expedia.ca/Greenville-Hotels-3-Mi-To-Dtwn-Modern-Cottage-In-Greenville.h111929202.Hotel-Information)

Cottage

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/104000000/103710000/103707900/103707807/784635bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/104000000/103710000/103707900/103707807/6c10521c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/104000000/103710000/103707900/103707807/1767b060.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/104000000/103710000/103707900/103707807/09b84ce7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Waterfront Seneca Cabin \~ 4 Mi to Boat Launch!

[](https://www.expedia.ca/Seneca-Hotels-Waterfront-Seneca-Cabin-4-Mi-To-Boat-Launch.h103707807.Hotel-Information)

Seneca

10/10

Exceptional

(1 review)

"Beautiful and quaint cabin! Highly recommend, great view of the lake."

[](https://www.expedia.ca/Seneca-Hotels-Waterfront-Seneca-Cabin-4-Mi-To-Boat-Launch.h103707807.Hotel-Information)

Cottage

![Cottage (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/95000000/94970000/94965700/94965665/b9728109.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cottage (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/95000000/94970000/94965700/94965665/8108d915.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cottage (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/95000000/94970000/94965700/94965665/91d5d964.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cottage (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/95000000/94970000/94965700/94965665/8b275f49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Claires Cottage \~ 4 Mi to Downtown Greenville!

[](https://www.expedia.ca/Greenville-Hotels-Charming-Cottage-4-Mi-To-Downtown-Greenville.h94965665.Hotel-Information)

Greenville

10/10

Exceptional

(1 review)

"Great trip. The small cottage was perfect for my wife and I and the owner was very responsive."

[](https://www.expedia.ca/Greenville-Hotels-Charming-Cottage-4-Mi-To-Downtown-Greenville.h94965665.Hotel-Information)

Cottage

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98550000/98548800/98548744/ce6330d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (2 Bedrooms) | Front of property](https://images.trvl-media.com/lodging/99000000/98550000/98548800/98548744/925daccc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98550000/98548800/98548744/f306db0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98550000/98548800/98548744/6f31060d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Updated Greenville Home w/ Backyard!

[](https://www.expedia.ca/Greenville-Hotels-Updated-Greenville-Home-W-Backyard.h98548744.Hotel-Information)

Greenville

10/10

Exceptional

(2 reviews)

[](https://www.expedia.ca/Greenville-Hotels-Updated-Greenville-Home-W-Backyard.h98548744.Hotel-Information)

Cottage

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537127/e34f879b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537127/4964e86e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537127/54580926.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537127/664f7ac0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 9 Mi to Devils Fork State Park: Getaway w/ Porch!

[](https://www.expedia.ca/Tamassee-Hotels-Forested-Tamassee-Escape-W-Screened-Porch.h93537127.Hotel-Information)

Tamassee

10/10

Exceptional

(1 review)

"Fall weekend getaway and this was perfect location. Loved the back porch for coffee and views of the sun through all the colorful leaves. Felt like we were away from it all but just a short drive to restaurants, stores, lakes and parks!!!"

[](https://www.expedia.ca/Tamassee-Hotels-Forested-Tamassee-Escape-W-Screened-Porch.h93537127.Hotel-Information)

Cottage

![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119870000/119865300/119865212/83f2467b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119870000/119865300/119865212/72e7e252.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119870000/119865300/119865212/9010a905.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119870000/119865300/119865212/43ded798.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 8 Mi to Clemson: Peaceful Family Home w/ Yard

[](https://www.expedia.ca/Seneca-Hotels-8-Mi-To-Clemson-Peaceful-Family-Home-W-Yard.h119865212.Hotel-Information)

Seneca

10/10

Exceptional

(1 review)

"The place was all out perfect the owner was polite and perfect. It was a very peaceful place to stay thank you so much."

[](https://www.expedia.ca/Seneca-Hotels-8-Mi-To-Clemson-Peaceful-Family-Home-W-Yard.h119865212.Hotel-Information)

Cottage

![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/116000000/115590000/115584200/115584157/cbc428e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/116000000/115590000/115584200/115584157/f063ed32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/116000000/115590000/115584200/115584157/7bea9b1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/116000000/115590000/115584200/115584157/9bd47812.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Stay at Jos Taylor Retreat: 9 Mi to Greenville!

[](https://www.expedia.ca/Taylors-Hotels-Stay-At-Jos-Taylor-Retreat-9-Mi-To-Greenville.h115584157.Hotel-Information)

Taylors

10/10

Exceptional

(1 review)

"This rental is a time capsule that takes you back to Grandma and Grandpa's home. The owner is great to communicate with, as well as their property manager. Quaint older furniture, complete with blankets on the couches. There's all you need to cook and even a great cast-iron frying pan. I wish we had stayed here longer."

[](https://www.expedia.ca/Taylors-Hotels-Stay-At-Jos-Taylor-Retreat-9-Mi-To-Greenville.h115584157.Hotel-Information)

Cottage

![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/114000000/113190000/113184500/113184450/309d8bf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/114000000/113190000/113184500/113184450/ebe19f88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/114000000/113190000/113184500/113184450/34ff4e2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/114000000/113190000/113184500/113184450/86d9c4f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Deck, Grill & Dock Access: Lake Keowee Retreat!

[](https://www.expedia.ca/Seneca-Hotels-Deck.h113184450.Hotel-Information)

Seneca

10/10

Exceptional

(1 review)

"The best, perfect "

[](https://www.expedia.ca/Seneca-Hotels-Deck.h113184450.Hotel-Information)

[See all vacation rentals](https://expedia.ca/Hotel-Search?startDate=2026-04-23&endDate=2026-04-26&regionId=6057939&adults=2&sort=RECOMMENDED&stay_options_group=vacation_rentals_option&categorySearch=vacation_rentals_option&openPlayBack=true)

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## Stay near popular Southeastern United States attractions

!["Clemson University is an American public, coeducational, land-grant and sea-grant research university located in Clemson, South Carolina, United States.More clemson images:"](https://images.trvl-media.com/place/6127431/81e51bd8-6dfc-4739-9fb0-b15a1329fa3d.jpg)

### Clemson University

4.7/5 (738 reviews)

Enjoy the collegiate vibe when you visit Clemson University, during your travels in Clemson. Experience the area's theater scene or attend a football game. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6127431)

![Exploring Falls Park on the Reedy in Downtown Greenville, South Carolina during a peaceful afternoon stroll with scenic views](https://images.trvl-media.com/place/6082697/4d276125-b8b6-4bd4-9887-c71157164970.jpg)

### Falls Park on the Reedy

4.7/5 (1,399 reviews)

Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the acclaimed theater scene or attend a sporting event in this family-friendly area. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6082697)

![Nice little church with a beautiful Mountain view](https://images.trvl-media.com/place/553248621532656718/980f0b0b-1c20-45c2-a7ca-b2a7d56b195b.jpg)

Photo by Pon Xayavong Photography 

### Fred W. Symmes Chapel

4.8/5 (13 reviews)

You can find out about the history of Cleveland when you stop by Fred W. Symmes Chapel. Wander the lakeside and forest in this relaxing area. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621532656718)

### Haywood Mall

4.3/5 (952 reviews)

During your trip to Greenville, you can browse for the perfect souvenirs at Haywood Mall. Experience the great live music or attend a sporting event in this family-friendly area. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6130785)

### Bon Secours Wellness Arena

4.2/5 (601 reviews)

Catch an event at Bon Secours Wellness Arena during your trip to Greenville. Stroll along the riverfront or experience the acclaimed theater scene in this family-friendly area. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6082715)

### BMW Performance Center

4.7/5 (50 reviews)

You can spend an afternoon browsing the exhibits at BMW Performance Center during your travels in Greer. While in this family-friendly area, you can savor the charming coffeehouses. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6217409)

### Memorial Stadium

4.7/5 (201 reviews)

Catch an event at Memorial Stadium during your trip to Clemson. Experience the area's theater scene or attend a football game. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6193935)

## Learn more about Upstate South Carolina

Experience the family-friendly area of Upstate South Carolina—live music, restaurants, and sights from Frankie's Fun Park to The Shops at Greenridge.

[See all hotels in Upstate South Carolina](https://www.expedia.ca/Hotel-Search?startDate=2026-04-09&endDate=2026-04-10&adults=2&regionId=6057939)

![Greenville - Spartanburg](https://images.trvl-media.com/place/6035267/cb556cb0-09f4-48a1-92a0-474aceebaeea.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high)

Photo by Visit Greenville, South Carolina

## Top Upstate South Carolina Hotel Reviews

## Recent Reviews in Upstate South Carolina

![Hyatt Place Greenville/Haywood](https://images.trvl-media.com/lodging/1000000/70000/64600/64570/w3840h2556x0y3-09ad394d_y.jpg)

### Hyatt Place Greenville/Haywood

6/10 Okay

"My only complaint was really the noise and not as clean as I would have expected it to be, air conditioning unit was not very powerful and made it very stuffy and no air circulation so it kind of smelled funky, but overall it was a good stay "

[](https://expedia.ca/Greenville-Hotels-Hyatt-Place-GreenvilleHaywood.h64570.Hotel-Information)

![Hotel Hartness](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/91df3d0d_y.jpg)

### Hotel Hartness

10/10 Excellent

"Relaxing and beautiful property with many areas to explore, inside& out. "

[](https://expedia.ca/Greenville-Hotels-Hotel-Hartness.h89689223.Hotel-Information)

![Hilton Greenville](https://images.trvl-media.com/lodging/1000000/30000/23200/23172/8017eeff_y.jpg)

### Hilton Greenville

10/10 Excellent

"Property was very clean throughout stay. Very convenient to getting on/off highway. Minutes from downtown "

[](https://expedia.ca/Greenville-Hotels-Hilton-Greenville.h23172.Hotel-Information)

![Comfort Inn Greenville - Haywood Mall](https://images.trvl-media.com/lodging/1000000/30000/25000/24994/840ecd1b_y.jpg)

### Comfort Inn Greenville - Haywood Mall

8/10 Good

"Breakfast was really good"

[](https://expedia.ca/Greenville-Hotels-Comfort-Inn-Greenville-Haywood-Mall.h24994.Hotel-Information)

![Embassy Suites Greenville Golf Resort & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/b0e15e12_y.jpg)

### Embassy Suites Greenville Golf Resort & Conference Center

8/10 Good

"Clean room."

[](https://expedia.ca/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information)

![Mint House Greenville Downtown by Kasa](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/5e1376bb_y.jpg)

### Mint House Greenville Downtown by Kasa

10/10 Excellent

"Very clean and spacious "

[](https://expedia.ca/Greenville-Spartanburg-Hotels-Mint-House-Downtown-Greenville.h38593248.Hotel-Information)

![Best Western Plus Clemson Hotel & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3837h2558x3y3-4efd29d6_y.jpg)

### Best Western Plus Clemson Hotel & Conference Center

8/10 Good

"Everything was nice"

[](https://expedia.ca/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information)

![Hyatt Regency Greenville](https://images.trvl-media.com/lodging/1000000/30000/22300/22252/2e6ff142_y.jpg)

### Hyatt Regency Greenville

10/10 Excellent

"Check in was easy. Front desk staff was very friendly."

[](https://expedia.ca/Greenville-Hotels-Hyatt-Regency-Greenville.h22252.Hotel-Information)

![Best Western Plus Greenville I-385 Inn & Suites](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/f09ffe86_y.jpg)

### Best Western Plus Greenville I-385 Inn & Suites

10/10 Excellent

"Nice friendly staff, clean rooms, very efficient! Will use this location again!"

[](https://expedia.ca/Greenville-Hotels-Best-Western-Plus-Greenville-I-385-Inn-Suites.h23003.Hotel-Information)

## More cheap stays in Upstate South Carolina

![Urban Boutique Hotel, BW Signature Collection](https://images.trvl-media.com/lodging/1000000/30000/24400/24334/f974826b_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Urban Boutique Hotel, BW Signature Collection

536 Wade Hampton Blvd Greenville SC

CA $89

CA $98 total

Apr 12 - Apr 13

includes taxes & fees

8/10 Very Good! (979 reviews)

[](https://expedia.ca/Greenville-Hotels-Urban-Boutique-Hotel.h24334.Hotel-Information)

![Best Western Greenville Airport Inn](https://images.trvl-media.com/lodging/1000000/10000/800/708/w2678h1966x0y0-e3e18b8e_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Best Western Greenville Airport Inn

5009 Pelham Road Greenville SC

CA $99

CA $109 total

Mar 28 - Mar 29

includes taxes & fees

7.8/10 Good! (1,009 reviews)

[](https://expedia.ca/Greenville-Hotels-Best-Western-Greenville-Airport-Inn.h708.Hotel-Information)

![Comfort Inn Greenville - Haywood Mall](https://images.trvl-media.com/lodging/1000000/30000/25000/24994/840ecd1b_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Comfort Inn Greenville - Haywood Mall

246 Congaree Road Greenville SC

CA $105

CA $120 total

Apr 5 - Apr 6

includes taxes & fees

8/10 Very Good! (1,001 reviews)

[](https://expedia.ca/Greenville-Hotels-Comfort-Inn-Greenville-Haywood-Mall.h24994.Hotel-Information)

![Best Western Plus Greenville I-385 Inn & Suites](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/f09ffe86_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Best Western Plus Greenville I-385 Inn & Suites

831 Congaree Rd Greenville SC

CA $130

CA $143 total

Apr 5 - Apr 6

includes taxes & fees

9.2/10 Wonderful! (1,430 reviews)

[](https://expedia.ca/Greenville-Hotels-Best-Western-Plus-Greenville-I-385-Inn-Suites.h23003.Hotel-Information)

![Comfort Suites Greenville Airport](https://images.trvl-media.com/lodging/47000000/46120000/46116400/46116309/76f56d99_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Comfort Suites Greenville Airport

1371 Garlington Road Greenville SC

CA $136

CA $153 total

Apr 19 - Apr 20

includes taxes & fees

9.2/10 Wonderful! (1,009 reviews)

[](https://expedia.ca/Greenville-Spartanburg-Hotels-Comfort-Suites.h46116309.Hotel-Information)

![Best Western Plus Clemson Hotel & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3837h2558x3y3-4efd29d6_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Best Western Plus Clemson Hotel & Conference Center

1310 Tiger Blvd Clemson SC

CA $149

CA $165 total

Apr 1 - Apr 2

includes taxes & fees

8.2/10 Very Good! (1,000 reviews)

[](https://expedia.ca/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information)

## Hotels in Upstate South Carolina with star rating

![4 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/23700/23677/6ae928dd_z.jpg)

4 Star Hotels

11 properties

[](https://expedia.ca/4Star-Upstate-South-Carolina-Hotels.s40-0-d6057939.Travel-Guide-Filter-Hotels)

![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg)

3 Star Hotels

194 properties

[](https://expedia.ca/3Star-Upstate-South-Carolina-Hotels.s30-0-d6057939.Travel-Guide-Filter-Hotels)

![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg)

2 Star Hotels

316 properties

[](https://expedia.ca/2Star-Upstate-South-Carolina-Hotels.s20-0-d6057939.Travel-Guide-Filter-Hotels)

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- [Simpsonville Hotels ](https://www.expedia.ca/Simpsonville-Hotels.d6239.Travel-Guide-Hotels)
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- [West End Hotels ](https://www.expedia.ca/West-End-Greenville-Hotels.0-n6348163-0.Travel-Guide-Filter-Hotels)

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- [Greenville Convention Center ](https://www.expedia.ca/Greenville-Convention-Center-Greenville.d6125256.Vacation-Attraction)
- [Mauldin Vacations ](https://www.expedia.ca/Mauldin.d183944.Destination-Travel-Guides)
- [Prisma Health Greenville Memorial Hospital ](https://www.expedia.ca/Prisma-Health-Greenville-Memorial-Hospital-Greenville.d553248635941390934.Vacation-Attraction)
- [Terrace Shopping Center ](https://www.expedia.ca/Terrace-Shopping-Center-Greenville.d553248621563220413.Vacation-Attraction)

- [Car rentals near Prisma Health Greenville Memorial Hospital ](https://www.expedia.ca/Car-Rentals-In-Prisma-Health-Greenville-Memorial-Hospital.d553248635941390934.Car-Rental-Guide)

- [Book Hotels in Upstate South Carolina on Expedia.com ](https://www.expedia.com/Upstate-South-Carolina-Hotels.d6057939.Travel-Guide-Hotels)

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